Few road trips in America compare to the unforgettable drive along U.S. Route 1, the historic highway that stretches more than 2,300 miles along the East Coast before ending in the tropical paradise of the Florida Keys.

For travelers chasing ocean views, island culture, and a true coastal adventure, the most spectacular portion of this journey begins when US‑1 reaches South Florida and becomes the world‑famous Overseas Highway. From there, drivers cross turquoise waters and dozens of islands on their way to Key West.

This drive isn’t just transportation—it’s one of the most scenic road trips in the United States.

A Historic Highway Down the East Coast

U.S. Route 1 begins in Fort Kent, Maine, near the Canadian border. From there it travels south through many of the East Coast’s most well‑known cities before reaching Florida.

Major destinations along the route include:

  • Boston
  • New York City
  • Philadelphia
  • Washington, D.C.
  • Jacksonville
  • Miami

Before interstate highways existed, US‑1 served as the primary travel corridor along the Atlantic Coast. Today, it remains a favorite route for travelers looking to experience scenic coastal drives and historic communities.

The Overseas Highway: A Drive Over the Ocean

Once drivers leave the mainland south of Miami, US‑1 becomes the legendary Overseas Highway, a 113‑mile drive through the Florida Keys.

This breathtaking stretch connects 44 islands and crosses 42 bridges, creating one of the most unique driving experiences in the world.

Originally built on portions of the historic Overseas Railroad, the route was envisioned by railroad pioneer Henry Flagler in the early 1900s. Today, it remains one of Florida’s most famous attractions.

Travelers driving the Overseas Highway can expect:

  • endless ocean views on both sides of the road
  • spectacular sunrises and sunsets
  • world‑class fishing and boating
  • charming island communities
  • unique roadside stops and photo opportunities

Crossing the Famous Seven Mile Bridge

One of the most iconic moments of the journey is crossing the breathtaking Seven Mile Bridge, which connects Marathon to Little Duck Key.

This engineering marvel stretches nearly seven miles across open water, offering panoramic views of the Atlantic Ocean and the Gulf of Mexico. Many travelers say this is the moment the Florida Keys truly begin.

For a deeper look at the bridges that make this drive so unique, explore this related article:
Discover the Iconic Bridges of the Florida Keys

Discover the Hidden Gem of the Middle Keys

While many visitors rush straight to Key West, seasoned travelers know that the Middle Keys offer some of the most relaxing and beautiful areas in the island chain.

Communities like Islamorada, Marathon, and Key Colony Beach provide the perfect balance of island charm, outdoor adventure, and peaceful surroundings.

Visitors can enjoy:

  • snorkeling and diving in crystal-clear waters
  • kayaking and paddleboarding
  • deep-sea fishing charters
  • waterfront dining
  • quiet beaches and local wildlife

For anglers visiting the Keys, bridge fishing is a popular activity thanks to the many accessible fishing locations along the Overseas Highway:
Why Choose Bridge Fishing in the Keys

A Quiet Oceanfront Escape Just Off U.S. Route 1

When traveling along U.S. Route 1, many visitors look for a relaxing place to stay that offers easy access to the highway while still feeling secluded.

That’s exactly what you’ll find at Glunz Ocean Beach Hotel & Resort, located at mile marker 53.5 on the quiet island of Key Colony Beach.

Unlike many properties located directly along US‑1, the resort sits just a short distance away from the highway—tucked into a peaceful residential island community. This unique location allows guests to explore the Keys easily while enjoying a calm oceanfront setting without highway traffic noise.

Guests enjoy:

  • a rare private sandy beach
  • oceanfront suites and villas
  • two oceanfront heated pools and hot tub
  • kayaking, paddleboarding, and beach activities
  • walkable island dining and entertainment

For those simply passing through on a Keys road trip, the resort even offers day beach passes so visitors can relax by the beach and pool during their journey:
Day Beach Pass at Glunz Ocean Beach Hotel & Resort

Oceanfront Dining Along Your Road Trip

After a day exploring the islands along US‑1, travelers can unwind at Havana Jack’s Oceanside, located right next to the resort.

The restaurant features fresh seafood, Caribbean-inspired dishes, tropical cocktails, and live entertainment in a laid-back oceanside setting. With both indoor and outdoor seating overlooking the water, it’s a perfect place to relax and enjoy the Florida Keys sunset.

Frequently Asked Questions About Driving U.S. Route 1 in the Florida Keys

How long does it take to drive the Overseas Highway?

Driving the scenic stretch of U.S. Route 1 through the Florida Keys from Miami to Key West takes about 4 hours without stops, but most visitors spend an entire day exploring along the way.

What mile marker is Key Colony Beach?

The quiet island community of Key Colony Beach is located at Mile Marker 53.5, making it one of the most centrally located destinations in the Florida Keys. The island sits just off US‑1, offering travelers easy access to the Overseas Highway while remaining tucked away from highway traffic.

Where is a peaceful place to stay along U.S. Route 1?

Glunz Ocean Beach Hotel & Resort in Key Colony Beach provides a quiet oceanfront setting just off the highway, combining convenience with privacy and relaxing island vibes.

What makes the Overseas Highway one of the most scenic drives in the U.S.?

The highway connects 44 islands using 42 bridges, giving drivers uninterrupted ocean views, fishing opportunities, and iconic photo stops.

What is the most famous bridge on U.S. Route 1 in the Florida Keys?

The Seven Mile Bridge stretches more than six miles across open water, connecting Marathon to Little Duck Key, and is widely considered a highlight of any Keys road trip.

Helpful Florida Keys Travel Guides From Our Blog

Discover the Iconic Bridges of the Florida Keys
https://glunzoceanbeachhotel.com/discover-the-iconic-bridges-of-the-florida-keys/

Why Choose Bridge Fishing in the Keys
https://glunzoceanbeachhotel.com/why-choose-bridge-fishing-in-the-keys/

Discover the Best of Key Colony Beach, Florida Keys
https://glunzoceanbeachhotel.com/discover-the-best-of-key-colony-beach-florida-keys/

The History of Key Colony Beach: A Small Island With a Big Story
https://glunzoceanbeachhotel.com/the-history-of-key-colony-beach-florida-a-small-island-with-a-big-story/

Start Your Florida Keys Road Trip

Driving U.S. Route 1 through the Florida Keys isn’t just about reaching a destination—it’s about enjoying every mile of the journey.

From crossing the iconic Seven Mile Bridge to discovering hidden island communities like Key Colony Beach, the Overseas Highway delivers one of the most unforgettable road trips in America.

And when you’re ready to relax after a day of exploring, the peaceful oceanfront setting of Glunz Ocean Beach Hotel & Resort offers the perfect place to unwind and experience the true spirit of the Florida Keys.